BACKGROUNDNo gold standard exists in the world of scientific image acquisition; a proliferation of instruments each with its own proprietary data format has made out-of-the-box sharing of that data nearly impossible. In the field of light microscopy, the Bio-Formats library was designed to translate such proprietary data formats to a common, open-source schema, enabling sharing and reproduction of scientific results. While Bio-Formats has proved successful for microscopy images, the greater scientific community was lacking a domain-independent framework for format translation.
RESULTSSCIFIO (SCientific Image Format Input and Output) is presented as a freely available, open-source library unifying the mechanisms of reading and writing image data. The core of SCIFIO is its modular definition of formats, the design of which clearly outlines the components of image I/O to encourage extensibility, facilitated by the dynamic discovery of the SciJava plugin framework. SCIFIO is structured to support coexistence of multiple domain-specific open exchange formats, such as Bio-Formats’ OME-TIFF, within a unified environment.
CONCLUSIONSSCIFIO is a freely available software library developed to standardize the process of reading and writing scientific image formats.
SCIFIO: an extensible framework to support scientific image formats.
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Description: The substance Troglitazone is a ppargamma agonist. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mM in DMSO and to 10 mM in ethanol.
Description: The substance Troglitazone is a ppargamma agonist. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mM in DMSO and to 10 mM in ethanol.
Description: The substance VU0467154 is a m4 receptor agonist. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in DMSO.
Description: The substance Kainic acid is a kainate agonist. It is synthetically produced and has a purity of >99%. The pure substance is white powder which is May be dissolved in water (10 mg/ml).
Description: The substance Kainic acid is a kainate agonist. It is synthetically produced and has a purity of >99%. The pure substance is white powder which is May be dissolved in water (10 mg/ml).
Description: The substance Bexarotene is a retinoid rxr agonist. It is synthetically produced and has a purity of >98%. The pure substance is white powder which is soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml).
Description: The substance Bexarotene is a retinoid rxr agonist. It is synthetically produced and has a purity of >98%. The pure substance is white powder which is soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml).
Description: Anti-CD27 agonist antibody binds to CD27 on T cells and promotes T cell response. It represents new opportunities for cancer immunotherapy.
Description: Anti-CD27 agonist antibody binds to CD27 on T cells and promotes T cell response. It represents new opportunities for cancer immunotherapy.
Description: Recombinant monoclonal antibody recognizing human CD28. This antibody binds to CD28 on T cells and promotes T cell response. Not tested in other species. This antibody crosslinked with FcGR2B is useful for activation of CD27 costimulatory pathway in T cells.
Description: Recombinant monoclonal antibody recognizing human CD28. This antibody binds to CD28 on T cells and promotes T cell response. Not tested in other species.
Description: Anti-CD20 is a recombinant monoclonal antibody which features the constant region of the human IgG1 isotype and the variable region of rituximab. It binds to human CD20 extracellular region a.a 142- 184, where it acts asan agonist of the CD20 protein. Itis expressed in a 293 freestyle cell expression system and purified using protein A chromatography. MW = 150 kDa.
Description: Anti-CD137 recombinant human antibody recognizing the CD137 ligand binding region. This antibody not been tested for cross-reactivity with other species.
Description: Anti-CD137 recombinant human antibody recognizing the CD137 ligand binding region. This antibody not been tested for cross-reactivity with other species.
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Description: A polyclonal antibody against Defensin D2. Recognizes Defensin D2 from Spinacia oleracea. This antibody is Unconjugated. Tested in the following application: ELISA
Description: The substance Retinoic acid is a retinoid rar agonist. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mM in ethanol and 25 mM in DMSO.
Description: The substance Retinoic acid is a retinoid rar agonist. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mM in ethanol and 25 mM in DMSO.
Description: The substance Quisqualic Acid is a glutamate receptor agonist. It is isolated from quisqualis fructus and has a purity of 0.999. The pure substance is off white solid which is soluble to 100 mM in 1eq. NaOH; 10 mM in water.
Description: The substance Quisqualic Acid is a glutamate receptor agonist. It is isolated from quisqualis fructus and has a purity of 0.999. The pure substance is off white solid which is soluble to 100 mM in 1eq. NaOH; 10 mM in water.
