BACKGROUNDNo gold standard exists in the world of scientific image acquisition; a proliferation of instruments each with its own proprietary data format has made out-of-the-box sharing of that data nearly impossible. In the field of light microscopy, the Bio-Formats library was designed to translate such proprietary data formats to a common, open-source schema, enabling sharing and reproduction of scientific results. While Bio-Formats has proved successful for microscopy images, the greater scientific community was lacking a domain-independent framework for format translation.
RESULTSSCIFIO (SCientific Image Format Input and Output) is presented as a freely available, open-source library unifying the mechanisms of reading and writing image data. The core of SCIFIO is its modular definition of formats, the design of which clearly outlines the components of image I/O to encourage extensibility, facilitated by the dynamic discovery of the SciJava plugin framework. SCIFIO is structured to support coexistence of multiple domain-specific open exchange formats, such as Bio-Formats’ OME-TIFF, within a unified environment.
CONCLUSIONSSCIFIO is a freely available software library developed to standardize the process of reading and writing scientific image formats.
SCIFIO: an extensible framework to support scientific image formats.
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.
Troglitazone, a member of the thaizolidinediones, is an anti-diabetic and anti-inflammatory drug. It works by activating peroxisome proliferator-activated receptors (PPARs) (1). It is a ligand to both PPARalpha and gamma. It also contains an alpha-to
Description: The substance Troglitazone is a ppargamma agonist. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mM in DMSO and to 10 mM in ethanol.
Troglitazone, a member of the thaizolidinediones, is an anti-diabetic and anti-inflammatory drug. It works by activating peroxisome proliferator-activated receptors (PPARs) (1). It is a ligand to both PPARalpha and gamma. It also contains an alpha-to
Description: The substance Troglitazone is a ppargamma agonist. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mM in DMSO and to 10 mM in ethanol.
Allosteric activators of the M4 muscarinic acetylcholine receptor represent a novel approach for the treatment of psychotic symptoms associated with schizophrenia and other neuropsychiatric disorders. VU0467154 produced a robust dose-dependent revers
Description: The substance VU0467154 is a m4 receptor agonist. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in DMSO.
Kainic acid is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. It is a central nervous system stimulant and neurotoxin. It acts as a classic neuroexcitatory agent for induction of seizures in lab
Description: The substance Kainic acid is a kainate agonist. It is synthetically produced and has a purity of >99%. The pure substance is white powder which is May be dissolved in water (10 mg/ml).
Kainic acid is a conformationally restricted glutamate analog which acts as a selective agonist at kainate receptors. It is a central nervous system stimulant and neurotoxin. It acts as a classic neuroexcitatory agent for induction of seizures in lab
Description: The substance Kainic acid is a kainate agonist. It is synthetically produced and has a purity of >99%. The pure substance is white powder which is May be dissolved in water (10 mg/ml).
Bexarotene is a potent RXR agonist. It is able to permeate the blood-brain barrier. Bexarotene inhibits neurodegeneration and has anti-tumor properties.
Description: The substance Bexarotene is a retinoid rxr agonist. It is synthetically produced and has a purity of >98%. The pure substance is white powder which is soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml).
Bexarotene is a potent RXR agonist. It is able to permeate the blood-brain barrier. Bexarotene inhibits neurodegeneration and has anti-tumor properties.
Description: The substance Bexarotene is a retinoid rxr agonist. It is synthetically produced and has a purity of >98%. The pure substance is white powder which is soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml).
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.
Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against Defensin D2. Recognizes Defensin D2 from Spinacia oleracea. This antibody is Unconjugated. Tested in the following application: ELISA
Retinoic acid is a metabolite of Vitamin A that mediates the functions of vitamin A required for growth and development. It is generated in a specific region of the embryo during early embryonic development (1).
Description: The substance Retinoic acid is a retinoid rar agonist. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mM in ethanol and 25 mM in DMSO.
Retinoic acid is a metabolite of Vitamin A that mediates the functions of vitamin A required for growth and development. It is generated in a specific region of the embryo during early embryonic development (1).
Description: The substance Retinoic acid is a retinoid rar agonist. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mM in ethanol and 25 mM in DMSO.
Quisqualic acid is a glutamate receptor and AMPA ionotropic receptors agonist. It is also known to sensitize neurons in hippocampus to depolarization by L-AP6.
Description: The substance Quisqualic Acid is a glutamate receptor agonist. It is isolated from quisqualis fructus and has a purity of 0.999. The pure substance is off white solid which is soluble to 100 mM in 1eq. NaOH; 10 mM in water.
Quisqualic acid is a glutamate receptor and AMPA ionotropic receptors agonist. It is also known to sensitize neurons in hippocampus to depolarization by L-AP6.
Description: The substance Quisqualic Acid is a glutamate receptor agonist. It is isolated from quisqualis fructus and has a purity of 0.999. The pure substance is off white solid which is soluble to 100 mM in 1eq. NaOH; 10 mM in water.
BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP. This small molecule also exhibits partial agonist activity at P2X1 and P2Y1 receptors. Lastly, it can be used as a photoaffinity lab
Description: The substance BzATP is a prototypic p2x7 receptor agonist. It is synthetically produced and has a purity of >97.7%. The pure substance is off white solid which is soluble in water..
BzATP triethylammonium salt is a prototypic P2X7 receptor agonist that exhibits 5 - 10 fold greater potency than ATP. This small molecule also exhibits partial agonist activity at P2X1 and P2Y1 receptors. Lastly, it can be used as a photoaffinity lab
Description: The substance BzATP is a prototypic p2x7 receptor agonist. It is synthetically produced and has a purity of >97.7%. The pure substance is off white solid which is soluble in water..
Description: The substance WY-14643 is a ppar alpha agonist. It is synthetically produced and has a purity of 0.985. The pure substance is off white powder which is soluble in DMSO (40 mg/ml).
Description: The substance WY-14643 is a ppar alpha agonist. It is synthetically produced and has a purity of 0.985. The pure substance is off white powder which is soluble in DMSO (40 mg/ml).
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