SCIFIO: an extensible framework to support scientific image formats.

SCIFIO: an extensible framework to support scientific image formats.

BACKGROUNDNo gold standard exists in the world of scientific image acquisition; a proliferation of instruments each with its own proprietary data format has made out-of-the-box sharing of that data nearly impossible. In the field of light microscopy, the Bio-Formats library was designed to translate such proprietary data formats to a common, open-source schema, enabling sharing and reproduction of scientific results. While Bio-Formats has proved successful for microscopy images, the greater scientific community was lacking a domain-independent framework for format translation.

RESULTSSCIFIO (SCientific Image Format Input and Output) is presented as a freely available, open-source library unifying the mechanisms of reading and writing image data. The core of SCIFIO is its modular definition of formats, the design of which clearly outlines the components of image I/O to encourage extensibility, facilitated by the dynamic discovery of the SciJava plugin framework. SCIFIO is structured to support coexistence of multiple domain-specific open exchange formats, such as Bio-Formats’ OME-TIFF, within a unified environment.

CONCLUSIONSSCIFIO is a freely available software library developed to standardize the process of reading and writing scientific image formats.

 SCIFIO: an extensible framework to support scientific image formats.
SCIFIO: an extensible framework to support scientific image formats.

mGlu2 agonist

A3601-5.1 10 mM (in 1mL H2O)
EUR 506.4
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.

mGlu2 agonist

A3601-50 50 mg
EUR 2013.6
Description: LY2979165 is a novel potent agent that is used as Anti-depressants. LY2979165 is under clinical study. A Safety Study of LY2979165 is performing in Healthy Subjects. LY2979165 is useful for Anti-depressants.

Cyclin D2 (Cyclin D2) Antibody

20-abx111853
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Cyclin D2 (Cyclin D2) Antibody

20-abx012975
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Cyclin D2 (Cyclin D2) Antibody

20-abx225081
  • EUR 444.00
  • EUR 727.20
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 50 ul

Cyclin D2 (Cyclin D2) Antibody

abx232125-100ug 100 ug
EUR 610.8

Cyclin D2 (Cyclin D2) Antibody

abx448575-100ug 100 ug
EUR 627.6

Glucocorticoid receptor agonist

A3438-10 10 mg
EUR 1372.8
Description: Glucocorticoid receptor agonist is a potent Glucocorticoid receptor agonist.

Glucocorticoid receptor agonist

A3438-5 5 mg
EUR 752.4
Description: Glucocorticoid receptor agonist is a potent Glucocorticoid receptor agonist.

Glucocorticoid receptor agonist

A3438-5.1 10 mM (in 1mL DMSO)
EUR 822
Description: Glucocorticoid receptor agonist is a potent Glucocorticoid receptor agonist.

Wnt agonist 1

B6059-10 10 mg
EUR 164.4
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.

Wnt agonist 1

B6059-200 200 mg
EUR 901.2
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.

Wnt agonist 1

B6059-5.1 10 mM (in 1mL DMSO)
EUR 129.6
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.

Wnt agonist 1

B6059-50 50 mg
EUR 428.4
Description: Wnt agonist 1 is a small-molecule agonist of Wnt signaling pathway. The Wnt signaling pathway is an important signal transduction pathway that involved in a variety of physiological and pathological processes by regulating genes involved in cellular adhesion, proliferation, and differentiation.

TGR5 Receptor Agonist

B1185-10 10 mg
EUR 351.6
Description: TGR5 Receptor Agonist is a potent and selective agonist of TGR5 G-protein receptor with a pEC50 value of 6.8 in the U2-OS cell assay [1].

TGR5 Receptor Agonist

B1185-25 25 mg
EUR 686.4
Description: TGR5 Receptor Agonist is a potent and selective agonist of TGR5 G-protein receptor with a pEC50 value of 6.8 in the U2-OS cell assay [1].

TGR5 Receptor Agonist

B1185-5 5 mg
EUR 226.8
Description: TGR5 Receptor Agonist is a potent and selective agonist of TGR5 G-protein receptor with a pEC50 value of 6.8 in the U2-OS cell assay [1].

STING agonist-1

B7835-10 10 mg
EUR 309.6

STING agonist-1

B7835-50 50 mg
EUR 1120.8

TGR5 Receptor Agonist

HY-14229 100mg
EUR 1354.8

Glucocorticoid receptor agonist

HY-14234 10mg
EUR 1059.6

A2AR-agonist-1

HY-18776 100mg
EUR 3531.6

FPR Agonist 43

HY-19574 50mg
EUR 1106.4

STING agonist-1

HY-19711 100mg
EUR 3531.6

TLR7 agonist 2

HY-103039 10mg
EUR 1531.2

GPR40 agonist 4

HY-103083 100mg
EUR 1093.2

Pparδ agonist 2

HY-100120 1mg
EUR 1870.8

DREADD agonist 21

HY-100234 10mg
EUR 308.4

TPO agonist 1

HY-100380 10mM/1mL
EUR 297.6

PPAR agonist 1

HY-U00340 20mg
EUR 11317.2

GPR40 Agonist 2

HY-U00395 5mg
EUR 13828.8

STING agonist-3

HY-103665 5mg
EUR 542.4

GPR120 Agonist 2

HY-111353 100mg
EUR 2952

STING agonist-4

HY-123943 5mg
EUR 639.6

S1P1 Agonist III

HY-12835 10mg
EUR 308.4

Troglitazone (PPARgamma agonist)

SIH-260-10MG 10 mg
EUR 201.6
Description: The substance Troglitazone is a ppargamma agonist. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mM in DMSO and to 10 mM in ethanol.

Troglitazone (PPARgamma agonist)

SIH-260-50MG 50 mg
EUR 601.2
Description: The substance Troglitazone is a ppargamma agonist. It is synthetically produced and has a purity of >98%. The pure substance is white solid which is soluble to 100 mM in DMSO and to 10 mM in ethanol.

TGR5-Receptor-Agonist

B1635-25 each
EUR 582

TGR5-Receptor-Agonist

B1635-5 each
EUR 189.6

DREADD Agonist 21

B1924-1 each
EUR 157.2

DREADD Agonist 21

B1924-5 each
EUR 444

STING AGONIST G10

B2047-25 each
EUR 705.6

STING AGONIST G10

B2047-5 each
EUR 222

STING Agonist C11

B2398-1 each
EUR 222

STING Agonist C11

B2398-5 each
EUR 705.6

TGR5 Receptor Agonist

1722-5 each
EUR 405.6

Smo Agonist, SAG

1939-1 each
EUR 210

Smo Agonist, SAG

1939-5 each
EUR 652.8

Taq DNA Polymerase (Mg2+ plus Buffer, with dNTP)

P101-d2 5000 U
EUR 320.4

Taq DNA Polymerase (Mg2+ free Buffer, with dNTP)

P102-d2 5000 U
EUR 320.4

Champagne Taq DNA Polymerase

P122-d2 500 U (5 U/μl)
EUR 212.4

Taq Plus DNA Polmerase (with dNTP)

P201-d2 1000 U
EUR 231.6

Vazyme LAmp DNA Polymerase (Mg2+ plus buffer, with dNTP)

P301-d2 500 U
EUR 213.6

Vazyme LAmp DNA Polymerase (Mg2+ free buffer, with dNTP)

P302-d2 500 U
EUR 213.6

AceTaq DNA Polymerase

P401-d2 1000 U
EUR 272.4

Phanta Max Super-Fidelity DNA Polymerase

P505-d2 500 U
EUR 462

Cyclin D2 (Cyclin D2) Antibody (ALP)

abx445353-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (APC)

abx445354-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (Biotin)

abx445355-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (FITC)

abx445356-100ug 100 ug
EUR 678

Cyclin D2 (Cyclin D2) Antibody (HRP)

abx445357-100ug 100 ug
EUR 678

Cyclin D2 (Cyclin D2) Antibody (PerCP)

abx445359-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (RPE)

abx445360-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (Streptavidin)

abx445361-100ug 100 ug
EUR 693.6

Vitamin D2

20-abx184475
  • EUR 710.40
  • EUR 1496.40
  • EUR 460.80
  • 10 g
  • 25 g
  • 5 g

Rubiginone D2

GL3716-1MG 1 mg
EUR 247.2

Rubiginone D2

GL3716-5MG 5 mg
EUR 688.8

Vitamin D2

HY-76542 10mM/1mL
EUR 135.6

Platycodin D2

HY-N4087 5mg
EUR 384

Vitamin D2

GV6132-1G 1 g
EUR 93.6

Vitamin D2

GV6132-5G 5 g
EUR 237.6

Cyclin D2

PR27281 5 ug
EUR 229.2

Combretastatin D2

TBZ1184 unit Ask for price

Platycodin D2

TBZ2562 20mg Ask for price

Thrombin Receptor Agonist Peptide

A8668-1 1 mg
EUR 240
Description: Agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 ?M) and secretion.

Thrombin Receptor Agonist Peptide

A8668-10 10 mg
EUR 1341.6
Description: Agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 ?M) and secretion.

Thrombin Receptor Agonist Peptide

A8668-5 5 mg
EUR 781.2
Description: Agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 ?M) and secretion.

Thrombin Receptor Agonist Peptide

A8668-5.1 10 mM (in 1mL DMSO)
EUR 2720.4
Description: Agonist at the thrombin receptor; causes platelet aggregation (EC50 = 4 ?M) and secretion.

Orexin 2 Receptor Agonist

HY-19320 5mg
EUR 258

Ca2+ channel agonist 1

HY-41076 50mg
EUR 2539.2

S1p receptor agonist 1

HY-101265 50mg
EUR 2539.2

MC-4R Agonist 1

HY-U00396 1mg
EUR 5251.2

VU0467154 (M4 Receptor Agonist)

SIH-184-10MG 10 mg
EUR 352.8
Description: The substance VU0467154 is a m4 receptor agonist. It is synthetically produced and has a purity of >98%. The pure substance is tan solid which is soluble in DMSO.

Kainic acid (Kainate agonist)

SIH-364-10MG 10 mg
EUR 261.6
Description: The substance Kainic acid is a kainate agonist. It is synthetically produced and has a purity of >99%. The pure substance is white powder which is May be dissolved in water (10 mg/ml).

Kainic acid (Kainate agonist)

SIH-364-50MG 50 mg
EUR 878.4
Description: The substance Kainic acid is a kainate agonist. It is synthetically produced and has a purity of >99%. The pure substance is white powder which is May be dissolved in water (10 mg/ml).

Bexarotene (Retinoid RXR agonist)

SIH-535-100MG 100 mg
EUR 238.8
Description: The substance Bexarotene is a retinoid rxr agonist. It is synthetically produced and has a purity of >98%. The pure substance is white powder which is soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml).

Bexarotene (Retinoid RXR agonist)

SIH-535-10MG 10 mg
EUR 164.4
Description: The substance Bexarotene is a retinoid rxr agonist. It is synthetically produced and has a purity of >98%. The pure substance is white powder which is soluble in DMSO (60 mg/ml) or ethanol (warm, 10 mg/ml).

Orexin 2 Receptor Agonist

B1124-25 each
EUR 770.4

Orexin 2 Receptor Agonist

B1124-5 each
EUR 248.4

EZSolution? TGR5 Receptor Agonist

2538-5 each
EUR 392.4

Smo agonist, SAG dihydrochloride

2801-1 each
EUR 301.2

Smo agonist, SAG dihydrochloride

2801-5 each
EUR 901.2

Anti-CD27 Agonist Antibody

100111-1 50 µg
EUR 335
Description: Anti-CD27 agonist antibody binds to CD27 on T cells and promotes T cell response. It represents new opportunities for cancer immunotherapy.

Anti-CD27 Agonist Antibody

100111-2 100 µg
EUR 460
Description: Anti-CD27 agonist antibody binds to CD27 on T cells and promotes T cell response. It represents new opportunities for cancer immunotherapy.

Anti-CD28 Agonist Antibody

100182-1 50 µg
EUR 335
Description: Recombinant monoclonal antibody recognizing human CD28. This antibody binds to CD28 on T cells and promotes T cell response. Not tested in other species. This antibody crosslinked with FcGR2B is useful for activation of CD27 costimulatory pathway in T cells.

Anti-CD28 Agonist Antibody

100182-2 100 µg
EUR 460
Description: Recombinant monoclonal antibody recognizing human CD28. This antibody binds to CD28 on T cells and promotes T cell response. Not tested in other species.

Anti- CD20 Agonist Antibody

71209 100 µg
EUR 325
Description: Anti-CD20 is a recombinant monoclonal antibody which features the constant region of the human IgG1 isotype and the variable region of rituximab. It binds to human CD20 extracellular region a.a 142- 184, where it acts asan agonist of the CD20 protein. Itis expressed in a 293 freestyle cell expression system and purified using protein A chromatography. MW = 150 kDa.

Anti-CD3 Agonist Antibody

71274-1 50 µg
EUR 355
Description: Recombinant human antibody recognizing the CD3 binding region on immune cells.

Anti-CD3 Agonist Antibody

71274-2 100 µg
EUR 510
Description: Recombinant human antibody recognizing the CD3 binding region on immune cells.

Anti-CD137 Agonist Antibody

79097-1 50 µg
EUR 335
Description: Anti-CD137 recombinant human antibody recognizing the CD137 ligand binding region. This antibody not been tested for cross-reactivity with other species.

Anti-CD137 Agonist Antibody

79097-2 100 µg
EUR 460
Description: Anti-CD137 recombinant human antibody recognizing the CD137 ligand binding region. This antibody not been tested for cross-reactivity with other species.

Cyclin D2 (Cyclin D2) Antibody (ATTO 390)

abx445345-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (ATTO 488)

abx445346-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (ATTO 565)

abx445347-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (ATTO 594)

abx445348-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (ATTO 633)

abx445349-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (ATTO 655)

abx445350-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (ATTO 680)

abx445351-100ug 100 ug
EUR 693.6

Cyclin D2 (Cyclin D2) Antibody (ATTO 700)

abx445352-100ug 100 ug
EUR 693.6

Cyclin-D2/ Rat Cyclin- D2 ELISA Kit

ELA-E0586r 96 Tests
EUR 1063.2

Human Cyclin-D2(Cyclin-D2)ELISA Kit

YLA0602HU-48T 48T
EUR 435

Human Cyclin-D2(Cyclin-D2)ELISA Kit

YLA0602HU-96T 96T
EUR 562.5

Cyclin D2 (Cyclin D2) Antibody (PE/ATTO 594)

abx445358-100ug 100 ug
EUR 710.4

Phospholipase D2 antibody

70R-50221 100 ul
EUR 344.4
Description: Purified Polyclonal Phospholipase D2 antibody

Cyclin D2 antibody

70R-34501 100 ug
EUR 392.4
Description: Rabbit polyclonal Cyclin D2 antibody

Cyclin D2 antibody

70R-13820 100 ug
EUR 386.4
Description: Affinity purified Rabbit polyclonal Cyclin D2 antibody

Cyclin D2 antibody

10R-7850 100 ug
EUR 386.4
Description: Mouse monoclonal Cyclin D2 antibody

Cyclin D2 antibody

10R-C149a 5 mL
EUR 344.4
Description: Mouse monoclonal Cyclin D2 antibody

Cyclin D2 antibody

10R-C149ax 100 ug
EUR 586.8
Description: Mouse monoclonal Cyclin D2 antibody

Sm-D2 Antibody

20-abx141931
  • EUR 444.00
  • EUR 727.20
  • EUR 360.00
  • 100 ul
  • 200 ul
  • 50 ul

Vitamin D2 (BSA)

20-abx165852
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Vitamin D2 (OVA)

20-abx165853
  • EUR 693.60
  • EUR 309.60
  • EUR 2013.60
  • EUR 811.20
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Vitamin D2 (Ergocalciferol)

A8543-1000 1 g
EUR 129.6
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.

Vitamin D2 (Ergocalciferol)

A8543-5.1 10 mM (in 1mL DMSO)
EUR 170.4
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.

Vitamin D2 (Ergocalciferol)

A8543-50 50 mg
EUR 115.2
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.

Vitamin D2 (Ergocalciferol)

A8543-5000 5 g
EUR 268.8
Description: Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.

Cyclin D2 Antibody

ABF5410 100 ug
EUR 525.6

Defensin D2 Antibody

20-abx319832
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Cyclin D2 Protein

20-abx260851
  • EUR 4101.60
  • EUR 393.60
  • EUR 276.00
  • 1 mg
  • 20 ug
  • 5 ug

Ivermectin B1a-d2

B5812-1 1 mg
EUR 673.2

Cyclin D2 Antibody

DF6608 200ul
EUR 420

Cyclin D2 Antibody

AF5410 200ul
EUR 420

Defensin D2 Antibody

1-CSB-PA305599LA01FKZ
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Defensin D2. Recognizes Defensin D2 from Spinacia oleracea. This antibody is Unconjugated. Tested in the following application: ELISA

Ganoderic acid D2

TBZ2690 10mg Ask for price

anti-Cyclin D2

YF-PA23377 50 ul
EUR 400.8
Description: Mouse polyclonal to Cyclin D2

anti-Phospholipase D2

YF-PA24393 50 ul
EUR 400.8
Description: Mouse polyclonal to Phospholipase D2

anti-Cyclin D2

YF-PA10727 50 ug
EUR 435.6
Description: Mouse polyclonal to Cyclin D2

anti-Cyclin D2

YF-PA10728 100 ul
EUR 483.6
Description: Rabbit polyclonal to Cyclin D2

anti-Cyclin D2

YF-PA10729 100 ug
EUR 483.6
Description: Rabbit polyclonal to Cyclin D2

pHiL- D2 Plasmid

PVT4033 2 ug
EUR 390

ABI D2 Lamp

LMP2000 EACH
EUR 442.32

Jasco D2 Lamp

LMP2018 EACH
EUR 383.04

Methylene chloride-d2

S-2481 1ML
EUR 76.38

Cyclin D2 Antibody

R30030 100 ug
EUR 419

PAR-4 Agonist Peptide, amide

HY-P1309 10mg
EUR 790.8

TLR7/8 agonist 1 (dihydrochloride)

HY-103698A 25mg
EUR 1575.6

GLP-1 receptor agonist 1

HY-112185 10mM/1mL
EUR 2467.2

GLP-1 receptor agonist 2

HY-112679 10mM/1mL
EUR 850.8

diABZI STING agonist-1 (trihydrochloride)

HY-112921B 10mM/1mL
EUR 1149.6

β cell proliferation agonist WS3

HY-12462 10mM/1mL
EUR 195.6

BH3 Interacting Domain Death Agonist

PR27259 2 ug
EUR 229.2

Retinoic acid (Retinoid RAR agonist)

SIH-258-250MG 250 mg
EUR 128.4
Description: The substance Retinoic acid is a retinoid rar agonist. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mM in ethanol and 25 mM in DMSO.

Retinoic acid (Retinoid RAR agonist)

SIH-258-50MG 50 mg
EUR 105.6
Description: The substance Retinoic acid is a retinoid rar agonist. It is synthetically produced and has a purity of >98%. The pure substance is yellow solid which is soluble to 50 mM in ethanol and 25 mM in DMSO.

Quisqualic Acid (Glutamate receptor agonist)

SIH-418-10MG 10 mg
EUR 306
Description: The substance Quisqualic Acid is a glutamate receptor agonist. It is isolated from quisqualis fructus and has a purity of 0.999. The pure substance is off white solid which is soluble to 100 mM in 1eq. NaOH; 10 mM in water.

Quisqualic Acid (Glutamate receptor agonist)

SIH-418-50MG 50 mg
EUR 991.2
Description: The substance Quisqualic Acid is a glutamate receptor agonist. It is isolated from quisqualis fructus and has a purity of 0.999. The pure substance is off white solid which is soluble to 100 mM in 1eq. NaOH; 10 mM in water.

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