Bioinformatics in Latin America and SoIBio impact, a tale of spin-off and expansion around genomes and protein structures.

Because of the impact arising from bioinformatics and computational biology, in this article, we present an overview of the history and current state of research in this field in Latin America (LA). It would be difficult to cover without inequality of all the efforts, initiatives and works that have occurred over the past two decades in this large region (which covers >> >> 19 million km2 and 600 million people). Despite the difficulties, we have to search in the field of analytical seek publicity carried out by researchers from 19 countries LA in the last 25 years. In this way, we find that research in bioinformatics in the region should develop twice as close to the average for the world’s scientific production in the field.

We also found some pioneering scientist who initiated and led bioinformatics in the region and the promoter of this new scientific field. Our analysis also reveals that the spin-off started around certain areas in the sciences of biomolecular: the study of the genome (anchored in a new generation of sequencing technologies in, followed by the development of proteomics) and the study of protein structure (supported by a three-dimensional structural technology determination and the progress of their computing).

Finally, we show that the contribution to this effort of the Iberoamerican Society for Bioinformatics, founded in Mexico in 2009, has been significant, because it is the leading forum to join the efforts of many scientists from LA interested in promoting research, training and education in bioinformatics.

Bioluminescence Cytotoxicity Assay Kit
55R-1367	Fitzgerald	500 assays	EUR 312
Description: Assay Kit for detection of Bioluminescence Cytotoxicity in the research laboratory

LDH Cytotoxicity Assay Kit
55R-1368	Fitzgerald	500 assays	EUR 570
Description: Assay Kit for detection of LDH Cytotoxicity in the research laboratory

CytoSelect LDH Cytotoxicity Assay Kit
CBA-241	Cell Biolabs	960 assays	EUR 403
Description: Cell Biolabs? CytoSelect LDH Cytotoxicity Assay Kit provides a colorimetric format for measuring and monitoring cell cytotoxicity.  The kit contains sufficient reagents for the evaluation of 960 assays in 96-well plates.  Cells can be plated and then treated with compounds or agents that affect cell viability.  Upon cell death, lactate dehydrogenase (LDH), a soluble enzyme found in the cytoplasm, is released into the growth media.  The growth media is then transferred to another plate and the released LDH is then detected with cytotoxicity reagent.  In the presence of lactate substrate (included in the LDH Cytotoxicity Reagent) LDH converts lactate to pyruvate and generates nicotinamide adenine dinucleotide (NADH).   The WST-1 molecule, also present in the LDH Cytotoxicity Reagent, is converted from WST-1 to the orange formazan form.  An increase in cell cytotoxicity is accompanied by increased LDH release and increased colorimetric signal.  The assay principles are basic and can be applied to most eukaryotic cell lines, including adherent and non-adherent cells and certain tissues, depending on LDH expression levels.  The LDH Cytotoxicity Reagent can be used to detect cytotoxicity in bacteria, yeast, fungi, protozoa as well as cultured mammalian and piscine cells.

LDH-Cytotoxicity Colorimetric Assay Kit
K2025-400	ApexBio	400 assays	EUR 390

AK Bioluminescence Cytotoxicity Assay Kit
K2026-500	ApexBio	500 assays	EUR 266

LDH-Cytotoxicity Colorimetric Assay Kit
K311-400	Biovision		EUR 387

CytoSelect Cell Viability and Cytotoxicity Assay
CBA-240	Cell Biolabs	96 assays	EUR 392
Description: The CytoSelect Cell Viability and Cytotoxicity Assay Kit provides a simple format for monitoring cell viability via metabolic activity. Live cells are detected with either MTT (colorimetric detection) or Calcein AM (fluorometric detection). Dead cells are detected by EthD-1 reagent (fluorometric). All 3 detection reagents are included, along with Saponin (a cell death initiator). Prior to the assay, cells may be treated with compounds or agents that affect cell viability. This kit is suitable for eukaryotic cells, not yeast or bacteria.

LDH-Cytotoxicity Colorimetric Assay Kit II
K2027-500	ApexBio	500 assays	EUR 418

LDH-Cytotoxicity Colorimetric Assay Kit II
K313-500	Biovision		EUR 419

PicoProbe? LDH-Cytotoxicity Fluorometric Assay Kit
K314-500	Biovision		EUR 419

Crystal Violet Cell Cytotoxicity Assay Kit
K329-1000	Biovision		EUR 316

Neutral Red Cell Cytotoxicity Assay Kit
K447-1000	Biovision		EUR 316

Acid Phosphatase Cell Cytotoxicity Assay Kit
K937-500	Biovision		EUR 370

MTT Cell Proliferation and Cytotoxicity Assay Kit
AR1156	BosterBio	1 kit (for 500 assays)	EUR 96

CytoX-Red Cell Proliferation/Cytotoxicity Assay Kit
OP-0004	EpiGentek	10x96 assays	EUR 395.1
Description: reagents widely cited

CytoX-Violet Cell Proliferation/Cytotoxicity Assay Kit
OP-0005	EpiGentek	20x96 assays	EUR 395.1
Description: fast delivery possible

MTT Cell Proliferation and Cytotoxicity Assay Kit
abx090676-500tests	Abbexa	500 tests	EUR 237

Cell Proliferation and Cytotoxicity MTT Assay Kit
C0210-100	GenDepot	100 Assays	EUR 165

Cell Proliferation and Cytotoxicity MTT Assay Kit
C0210-500	GenDepot	500 Assays	EUR 300

Cell Proliferation and Cytotoxicity MTT Assay Kit
C0210-501	GenDepot	5000 Assays	EUR 1238

QuantiChrom? LDH Cytotoxicity Assay Kit (C2LD-100)
C2LD-100	Cusabio	100	EUR 127.43
Description: Quantitative determination of cytotoxicity based on cellular lactate dehydrogenase release into cell culture medium by colorimetric (565nm) method. Procedure: 30 min. Kit size: 100 tests. Detection limit: 2 U/L. Shelf life: 6 months. Shipping: ambient tem

WST-NR-CV Combined Cytotoxicity Assay Kit
K543-1000	Biovision		EUR 675

Sulforhodamine B Cell Cytotoxicity Assay Kit (Colorimetric)
K943-1000	Biovision		EUR 316

Neutral Red Cell Proliferation and Cytotoxicity Assay Kit
AR1157	BosterBio	1 kit (for 500 assays)	EUR 101

WST-1 Cell Proliferation and Cytotoxicity Assay Kit
AR1158	BosterBio	1 kit (for 100 assays)	EUR 86

WST-1 Cell Proliferation and Cytotoxicity Assay Kit
AR1159	BosterBio	1 kit (for 500 assays)	EUR 131

Cell Meter™ Colorimetric Cell Cytotoxicity Assay Kit
22780	AAT Bioquest	1000 Tests	EUR 219

Cell Meter™ Fluorimetric Cell Cytotoxicity Assay Kit
22781	AAT Bioquest	1000 Tests	EUR 219

Cell Cytotoxicity Assay Kit II (WST-SRB-Crystal Violet)
K173-1000	Biovision		EUR 707

Cell-Mediated Cytotoxicity Fluorometric Assay Kit (7-AAD/CFSE)
K315-100	Biovision		EUR 327

Viability/Cytotoxicity Assay kit for Bacteria Live and Dead Cells
30027	Biotium	1KIT	EUR 356
Description: Minimum order quantity: 1 unit of 1KIT

Cytotoxicity Control (saponin)
Z5030008	Biochain	50 mg	EUR 249
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.

Basic Cytotoxicity Test Kits
CT17001	Neuromics	125 Tests	EUR 409

Basic Cytotoxicity Test Kits
CT17002	Neuromics	250 Tests	EUR 650

Total Cytotoxicity Test Kits
CT17003	Neuromics	125 Tests	EUR 513

Total Cytotoxicity Test Kits
CT17004	Neuromics	250 Tests	EUR 813

Cytotoxicity Control Reagent (Saponin)
CTTX-050	BioAssay Systems	(50mg)	EUR 135
Description: To be used as a cytotoxic control agent in the CellQuanti-BlueTM and CellQuanti-MTTTM Cell Viability Assay Kits. IC50 = 0.002 wt%. Kit size: (50mg) tests. Shelf life: 12 months. Shipping: ambient temp; storage: 4°C.

Natural Cytotoxicity Receptor NKp46 Antibody
20-abx137389	Abbexa	EUR 704.00 EUR 328.00 EUR 230.00	100 ug 20 ug 5 ug

Natural Cytotoxicity Receptor NKp46 Protein
20-abx261725	Abbexa	EUR 3530.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug

Recombinant Human Natural Cytotoxicity Receptor NKp46
7-05710	CHI Scientific	5µg	Ask for price

Recombinant Human Natural Cytotoxicity Receptor NKp46
7-05711	CHI Scientific	20µg	Ask for price

Recombinant Human Natural Cytotoxicity Receptor NKp46
7-05712	CHI Scientific	1mg	Ask for price

Natural Cytotoxicity Receptor NKp46 Human Recombinant Protein
PROTO76036	BosterBio	Regular: 20ug	EUR 317
Description: NKp46 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 235 amino acids and having a molecular mass of 26.6 kDa.

Natural Cytotoxicity Triggering Receptor 1 (CD335) Antibody
20-abx133776	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx130832	Abbexa	EUR 439.00 EUR 133.00 EUR 1233.00 EUR 592.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx130833	Abbexa	EUR 425.00 EUR 133.00 EUR 1177.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Antibody
20-abx130834	Abbexa	EUR 411.00 EUR 133.00 EUR 1149.00 EUR 565.00 EUR 314.00	100 ug 10 ug 1 mg 200 ug 50 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx130835	Abbexa	EUR 439.00 EUR 133.00 EUR 1233.00 EUR 592.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx130836	Abbexa	EUR 411.00 EUR 133.00 EUR 1149.00 EUR 565.00 EUR 314.00	100 ug 10 ug 1 mg 200 ug 50 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx119002	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Natural Cytotoxicity Triggering Receptor 2 (CD336) Antibody
20-abx123227	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Antibody
20-abx114027	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul

Natural Cytotoxicity Triggering Receptor 1 (CD335) Antibody
20-abx008420	Abbexa	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx004931	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx005398	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul

Natural Cytotoxicity Triggering Receptor 1 (CD335) Antibody
abx414080-05mg	Abbexa	0.5 mg	EUR 829

Natural Cytotoxicity Triggering Receptor 1 (CD335) Antibody
abx414081-01mg	Abbexa	0.1 mg	EUR 453

Natural Cytotoxicity Triggering Receptor 1 (CD335) Antibody
abx415254-05mg	Abbexa	0.5 mg	EUR 829

Natural Cytotoxicity Triggering Receptor 1 (CD335) Antibody
abx415256-01mg	Abbexa	0.1 mg	EUR 439

Natural Cytotoxicity Triggering Receptor 1 (CD335) Antibody
abx415295-01mg	Abbexa	0.1 mg	EUR 453

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Protein
20-abx261242	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Protein
20-abx261277	Abbexa	EUR 3418.00 EUR 328.00 EUR 230.00	1 mg 20 ug 5 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx270072	Abbexa	EUR 467.00 EUR 537.00 EUR 272.00 EUR 815.00 EUR 356.00	100 tests 200 tests 25 tests 500 tests 50 tests

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Antibody
20-abx322054	Abbexa	EUR 439.00 EUR 328.00	100 ul 50 ul

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx323433	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx323434	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Antibody
20-abx323755	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Natural Cytotoxicity Triggering Receptor 1 (NKp46) Antibody
abx217074-100ug	Abbexa	100 ug	EUR 439

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Antibody
abx217075-100ug	Abbexa	100 ug	EUR 439

Natural Cytotoxicity Triggering Receptor 2 (CD336) Antibody
abx231468-100ug	Abbexa	100 ug	EUR 551

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx339912	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Antibody
20-abx339913	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Natural Cytotoxicity Triggering Receptor 2 (NCR2) Antibody
20-abx339914	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx249454	Abbexa	EUR 314.00 EUR 98.00 EUR 398.00 EUR 495.00	100 ug 10 ug 200 ug 300 µg

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx211846	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx173727	Abbexa	EUR 829.00 EUR 439.00	1 mg 200 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx210873	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx210874	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul

Natural Cytotoxicity Receptor NKp46 Mouse Recombinant Protein
PROTQ8C567	BosterBio	Regular: 5ug	EUR 317
Description: NKp46 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 481 amino acids (17-255 a.a) and having a molecular mass of 54.4kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).;NKp46 is fused to a 239 amino acid hIgG-His Tag at C-terminus & purified by proprietary chromatographic techniques.

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx330127	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx330156	Abbexa	EUR 314.00 EUR 244.00	100 ug 50 ug

Natural Cytotoxicity Triggering Receptor 3 (NCR3) Antibody
20-abx334059	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Natural Cytotoxicity Triggering Receptor 1 (NCR1) Antibody
20-abx333883	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug

Campylobacter pylori Cytotoxicity-associated immunodominant antigen (cagA)
1-CSB-YP345531HUV	Cusabio	EUR 679.00 EUR 335.00 EUR 2172.00 EUR 1051.00 EUR 1442.00 EUR 435.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Campylobacter pylori Cytotoxicity-associated immunodominant antigen(cagA),partial expressed in Yeast

Helicobacter pylori Cytotoxicity-associated immunodominant antigen (cagA)
1-CSB-YP347068HUS	Cusabio	EUR 679.00 EUR 335.00 EUR 2172.00 EUR 1051.00 EUR 1442.00 EUR 435.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Helicobacter pylori Cytotoxicity-associated immunodominant antigen(cagA),partial expressed in Yeast

Helicobacter pylori Cytotoxicity-associated immunodominant antigen (cagA)
1-CSB-EP301307HUS	Cusabio	EUR 611.00 EUR 309.00 EUR 1827.00 EUR 939.00 EUR 1218.00 EUR 397.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Helicobacter pylori Cytotoxicity-associated immunodominant antigen(cagA),partial expressed in E.coli

Campylobacter pylori Cytotoxicity-associated immunodominant antigen (cagA)
1-CSB-EP345531HUV	Cusabio	EUR 611.00 EUR 309.00 EUR 1827.00 EUR 939.00 EUR 1218.00 EUR 397.00	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Campylobacter pylori Cytotoxicity-associated immunodominant antigen(cagA),partial expressed in E.coli

Recombinant Natural Cytotoxicity Triggering Receptor 1 (NCR1)
4-RPB800Mu01	Cloud-Clone	EUR 386.72 EUR 206.00 EUR 1175.20 EUR 458.40 EUR 816.80 EUR 322.00 EUR 2788.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Mouse Natural Cytotoxicity Triggering Receptor 1 expressed in: E.coli

Recombinant Natural Cytotoxicity Triggering Receptor 1 (NCR1)
4-RPB800Ra01	Cloud-Clone	EUR 359.84 EUR 199.00 EUR 1074.40 EUR 424.80 EUR 749.60 EUR 304.00 EUR 2536.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Natural Cytotoxicity Triggering Receptor 1 expressed in: E.coli

Recombinant Natural Cytotoxicity Triggering Receptor 2 (NCR2)
4-RPB803Hu01	Cloud-Clone	EUR 377.76 EUR 204.00 EUR 1141.60 EUR 447.20 EUR 794.40 EUR 316.00 EUR 2704.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Natural Cytotoxicity Triggering Receptor 2 expressed in: E.coli

Recombinant Natural Cytotoxicity Triggering Receptor 3 (NCR3)
4-RPB804Hu01	Cloud-Clone	EUR 413.60 EUR 214.00 EUR 1276.00 EUR 492.00 EUR 884.00 EUR 340.00 EUR 3040.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Human Natural Cytotoxicity Triggering Receptor 3 expressed in: E.coli

Recombinant Natural Cytotoxicity Triggering Receptor 3 (NCR3)
4-RPB804Ra01	Cloud-Clone	EUR 449.44 EUR 223.00 EUR 1410.40 EUR 536.80 EUR 973.60 EUR 364.00 EUR 3376.00	100 ug 10ug 1 mg 200 ug 500 ug 50ug 5 mg
Description: Recombinant Rat Natural Cytotoxicity Triggering Receptor 3 expressed in: E.coli

Recombinant (E.Coli) Human Natural Cytotoxicity Receptor NKp46
RP-880	Alpha Diagnostics	5 ug	EUR 164

Autophagy/Cytotoxicity Dual Staining Kit (Cell-Based)
K449-50	Biovision		EUR 544

Lysosomal Cytotoxicity Dual Staining Kit (Cell-Based)
K458-50	Biovision		EUR 572

XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)
30007	Biotium	1KIT	EUR 236
Description: Minimum order quantity: 1 unit of 1KIT