Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial.

Left ventricular (LV) dysfunction c-kit-positive, lineage-negative cardiac stem cells (CSC) improving post-infarction when given to animals. We conducted an experiment phase 1 (Stem Cell Infusion in Patients with ischemic cardiomyopathy [Scipio]) from autologous CSC for the treatment of heart failure due to ischemic heart disease.In trial stage A Scipio, patients with post-infarction LV dysfunction (ejection fraction [EF] ≤ 40%) prior to coronary artery bypass grafting were consecutively enrolled in the treatment and control groups. In stage B, patients were randomly assigned to treatment or control groups in a ratio of 2: 3 by using the block scheme of computer-generated randomization. 1 million autologous CSC given by intracoronary infusion at an average of 113 days (SE 4) after surgery; untreated controls.

Although this study is an open label, echocardiographic analysis did not know the duties of the group. The primary endpoint was a short-term security of CSC and the secondary endpoint was efficacy. A per-protocol analysis were used. This study is registered with ClinicalTrials.gov, number NCT00474461.This study is still in progress. 16 patients were assigned to the treatment group and seven for the control group; no side effects were reported related CSC.

On 14 CSC-treated patients were analyzed, LVEF increased from 30 · 3% (SE 1 · 9) before CSC infusion to 38 · 5% (2 · 8) at 4 months after infusion (p = 0 · 001). In contrast, the seven control patients, as long as the appropriate time interval, LVEF did not change (30 · 1% [2 · 4] at 4 months after CABG vs 30 · 2% [2 · 5] at 8 months after CABG). Importantly, CSC healthful effects are even more pronounced in the first year in eight patients (eg, LVEF increased by 12 · 3 unit ejection fraction [2 · 1] vs baseline, p = 0 · 0007).

In seven patients treated in whom cardiac MRI can be done, infarct size decreased from 32 · 6 g (6 · 3) by 7 · 8 g (1 · 7; 24%) at 4 months (p = 0 · 004) and 9 · 8 g (3 · 5; 30%) at 1 year (p = 0 · 04) .This preliminary results in patients with very encouraging. They suggest that intracoronary infusion of autologous CSC effective in improving LV systolic function and reduced infarct size in patients with heart failure after myocardial infarction, and warrant further, larger, phase 2 studies.University of Louisville Research Foundation and the National Institutes of Health ,

(Rac)-Luciferin 6′-methyl ether (sodium)

HY-115749A Get quote Ask for price
Description: D-Luciferin 6′-methyl ether (6′-Methoxyluciferin; compound 19a) sodium is a potent luciferase from the North American firefly Photinus pyralis (PpyLuc) inhibitor with an IC50 of 0.1 μM. D-Luciferin 6′-methyl ether, a D-luciferin analog, shows non-specific interactions at ATP- and luciferin-binding sites of the PpyLuc active site[1].

D-Luciferin, Sodium Salt

7902-100 each
EUR 144

D-Luciferin, Sodium Salt

7902-10G each
EUR 2890.8

D-Luciferin, Sodium Salt

7902-10PK each
EUR 3315.6

D-Luciferin, Sodium Salt

7902-1G each
EUR 424.8

D-Luciferin, Sodium Salt

7902-25G each Ask for price

D-Luciferin, Sodium Salt

7902-3PK each
EUR 1110

D-Luciferin, Sodium Salt

7902-50G each Ask for price

D-Luciferin, Sodium Salt

7902-5PK each
EUR 1795.2

D-Luciferin, SODIUM SALT

10102-1 50MG
EUR 86
Description: N/A

D-Luciferin, SODIUM SALT

10102-1-1 EA
EUR 232

D-Luciferin, SODIUM SALT

10102-2 1G
EUR 799
Description: N/A

D-Luciferin, SODIUM SALT

10102-2-1 EA
EUR 799

D-Luciferin sodium salt

B8311-10 10 mg
EUR 48
Description: The substrate of firefly luciferase

D-Luciferin sodium salt

B8311-200 200 mg
EUR 344
Description: The substrate of firefly luciferase

D-Luciferin sodium salt

B8311-50 50 mg
EUR 128
Description: The substrate of firefly luciferase

D-Luciferin sodium salt

GP8979 25mg
EUR 284.45

D-Luciferin (sodium salt)

HY-12591 50mg
EUR 183.6

D-Luciferin sodium salt

GP8979-100 100
EUR 310.6

D-Luciferin sodium salt

GP8979-25 25
EUR 113.1

D-Luciferin, sodium salt

MBS8579911-100mg 100mg
EUR 290

D-Luciferin, sodium salt

MBS8579911-1g 1g
EUR 835

D-Luciferin, sodium salt

MBS8579911-25mg 25mg
EUR 195

D-Luciferin, sodium salt

MBS8579911-5x100mg 5x100mg
EUR 1245

D-Luciferin, sodium salt

MBS8579911-5x25mg 5x25mg
EUR 820

D-Luciferin sodium salt

MBS3846184-100mg 100mg
EUR 365

D-Luciferin sodium salt

MBS3846184-10mg 10mg
EUR 135

D-Luciferin sodium salt

MBS3846184-25mg 25mg
EUR 180

D-Luciferin sodium salt

MBS3846184-50mg 50mg
EUR 245

D-Luciferin sodium salt

MBS3846184-5x100mg 5x100mg
EUR 1630

D-Luciferin Sodium Salt ex. Firefly, 99%

62851 25 Mg
EUR 40.95
Description: Part B

D-Luciferin,-sodium-salt

E37F12509 1-g
EUR 1333.33
Description: Reagents-for-in-vivo-imaging.Bioluminescence-reagent.

Luciferin D-, Firefly, Potassium Salt (4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid Potassium, D-Luciferin)

MBS639256-100mg 100mg
EUR 470

Luciferin D-, Firefly, Potassium Salt (4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid Potassium, D-Luciferin)

MBS639256-1g 1g
EUR 1040

Luciferin D-, Firefly, Potassium Salt (4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid Potassium, D-Luciferin)

MBS639256-500mg 500mg
EUR 680

Luciferin D-, Firefly, Potassium Salt (4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid Potassium, D-Luciferin)

MBS639256-50mg 50mg
EUR 290

Luciferin D-, Firefly, Potassium Salt (4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid Potassium, D-Luciferin)

MBS639256-5x1g 5x1g
EUR 4535

Luciferin

PCT1557-100MG 1 unit
EUR 318.64
Description: Luciferin

Luciferin

PCT1557-1G 1 unit
EUR 2760.87
Description: Luciferin

Luciferin

PCT1557-250MG 1 unit
EUR 764.83
Description: Luciferin

Luciferin

PCT1557-500MG 1 unit
EUR 1453.21
Description: Luciferin

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12509 25 mg
EUR 88
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12509-25mg 25 mg
EUR 86
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12510 100 mg
EUR 112
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12510-100mg 100 mg
EUR 109
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12511-1g 1 g
EUR 621
Description: Luciferin is the most popular and versatile bioluminescent substrate.

Latia luciferin

T32585-10mg 10mg Ask for price
Description: Latia luciferin

Latia luciferin

T32585-1g 1g Ask for price
Description: Latia luciferin

Latia luciferin

T32585-1mg 1mg Ask for price
Description: Latia luciferin

Latia luciferin

T32585-50mg 50mg Ask for price
Description: Latia luciferin

Latia luciferin

T32585-5mg 5mg Ask for price
Description: Latia luciferin

Latia luciferin

MBS5782154-INQUIRE INQUIRE Ask for price

Cypridina luciferin

T31154-10mg 10mg Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-1g 1g Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-1mg 1mg Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-50mg 50mg Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-5mg 5mg Ask for price
Description: Cypridina luciferin

Cypridina luciferin

MBS5780774-INQUIRE INQUIRE Ask for price

Luciferin-O-galactopyranoside

T32927-10mg 10mg Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-1g 1g Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-1mg 1mg Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-50mg 50mg Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-5mg 5mg Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

MBS5782492-5mg 5(mg
EUR 915

Luciferin-O-galactopyranoside

MBS5782492-5x5mg 5x5(mg
EUR 3970

Luciferase (Luciferin 4-monooxygenase) (AP)

MBS6248097-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (AP)

MBS6248097-5x01mL 5x0.1mL
EUR 3790

Luciferase (Luciferin 4-monooxygenase) (PE)

MBS6251982-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (PE)

MBS6251982-5x01mL 5x0.1mL
EUR 3790

2,4-D sodium salt

T40324-10mg 10mg Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-1g 1g Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-1mg 1mg Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-50mg 50mg Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-5mg 5mg Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

MBS5800588-5mg 5(mg
EUR 915

2,4-D sodium salt

MBS5800588-5x5mg 5x5(mg
EUR 3970

2,4-D (sodium salt)

HY-18572A Get quote Ask for price
Description: 2,4-D sodium salt (Sodium 2,4-dichlorophenoxyacetate) is a selective herbicide that can be orally active for the control of broad-leaved weeds. 2,4-D sodium salt can induce apoptosis. 2,4-D sodium salt inhibits DNA and protein synthesis, thereby preventing normal plant growth and development[1][2][3].

Luciferase (Luciferin 4-monooxygenase) (HRP)

MBS6251032-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (HRP)

MBS6251032-5x01mL 5x0.1mL
EUR 3790

Luciferase (Luciferin 4-monooxygenase) (APC)

MBS6268951-01mL 0.1mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (APC)

MBS6268951-5x01mL 5x0.1mL
EUR 3790

Luciferin 4-monooxygenase Antibody

MBS7191896-INQUIRE INQUIRE Ask for price

Luciferin 4-monooxygenase Antibody

MBS9012202-INQUIRE INQUIRE Ask for price

Luciferase (Luciferin 4-monooxygenase) (FITC)

MBS6250028-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (FITC)

MBS6250028-5x01mL 5x0.1mL
EUR 3790

Luciferase (Luciferin 4-monooxygenase) (Biotin)

MBS6249111-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (Biotin)

MBS6249111-5x01mL 5x0.1mL
EUR 3790

d-Cloprostenol Sodium Salt

C587330 10mg
EUR 293
Description: 62561-03-9

D-Luciferin Sodium

540277 50.0mg
EUR 180

D-Luciferin Sodium

T19743-10mg 10mg Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-1g 1g Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-1mg 1mg Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-50mg 50mg Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-5mg 5mg Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

MBS5756192-100mg 100mg
EUR 190

D-Luciferin Sodium

MBS5756192-10mg 10mg
EUR 145

D-Luciferin Sodium

MBS5756192-200mg 200mg
EUR 240

D-Luciferin Sodium

MBS5756192-50mg 50mg
EUR 160

D-Luciferin Sodium

MBS5756192-5x200mg 5x200mg
EUR 920

Coelenterazine, native (Luciferin, Preluciferin)

MBS654174-1mg 1mg
EUR 560

Coelenterazine, native (Luciferin, Preluciferin)

MBS654174-5x1mg 5x1mg
EUR 2375

Luciferase (Luciferin 4-monooxygenase) (MaxLight 490)

MBS6254046-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (MaxLight 490)

MBS6254046-5x01mL 5x0.1mL
EUR 3790

Luciferase (Luciferin 4-monooxygenase) (MaxLight 550)

MBS6255086-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (MaxLight 550)

MBS6255086-5x01mL 5x0.1mL
EUR 3790

Luciferase (Luciferin 4-monooxygenase) (MaxLight 405)

MBS6253006-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (MaxLight 405)

MBS6253006-5x01mL 5x0.1mL
EUR 3790

Luciferase (Luciferin 4-monooxygenase) (MaxLight 750)

MBS6257165-01mL 0.1mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (MaxLight 750)

MBS6257165-5x01mL 5x0.1mL
EUR 3790

Luciferase (Luciferin 4-monooxygenase) (MaxLight 650)

MBS6256126-01mL 0.1(mL
EUR 875

Luciferase (Luciferin 4-monooxygenase) (MaxLight 650)

MBS6256126-5x01mL 5x0.1mL
EUR 3790

StayBrite? Highly Stable Luciferase/Luciferin Reagent

K790-100 each
EUR 222

StayBrite? Highly Stable Luciferase/Luciferin Reagent

K790-1000 each
EUR 1005.6

StayBrite? Highly Stable Luciferase/Luciferin Reagent

K790-10000 each
EUR 6943.2

Firefly Luciferin 4-Monooxygenase (Recombinant)

20-abx073317
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 20 ug
  • 5 ug

Recombinant Firefly Luciferin 4-Monooxygenase

7-03073 5µg Ask for price

Recombinant Firefly Luciferin 4-Monooxygenase

7-03074 25µg Ask for price

Recombinant Firefly Luciferin 4-Monooxygenase

7-03075 1mg Ask for price

Luciferin 4-Monooxygenase Firefly Recombinant

rAP-1450 Inquiry Ask for price

Recombinant Firefly Luciferin 4-Monooxygenase

MBS144111-0005mg 0.005mg
EUR 240

Recombinant Firefly Luciferin 4-Monooxygenase

MBS144111-002mg 0.02mg
EUR 310

Recombinant Firefly Luciferin 4-Monooxygenase

MBS144111-1mg 1mg
EUR 2880

Recombinant Firefly Luciferin 4-Monooxygenase

MBS144111-5x1mg 5x1mg
EUR 12630

D,L-Alanosine Sodium Salt

A510795 250mg
EUR 161

Recombinant Luciferin 4 protein, His-tagged

Luciferin-4-3220H 25ug
EUR 255.2
Description: Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.

D-Mannuronic Acid Sodium Salt

D208470 1g
EUR 1200
Description: 921-56-2

D-Pantothenic Acid Sodium Salt

26004-02 25G
EUR 39.2

D-Pantothenic Acid Sodium Salt

26004-44 5G
EUR 19.25

D-Pantothenic Acid Sodium Salt

41600203-1 25 g
EUR 65.69

D-Pantothenic Acid Sodium Salt

41600203-2 100 g
EUR 169.05

D-Pantothenic Acid Sodium Salt

P190308 2.5g
EUR 80
Description: 867-81-2

D-Pantothenic acid sodium salt

MBS578469-100mg 100mg
EUR 145

D-Pantothenic acid sodium salt

MBS578469-200mg 200mg
EUR 160

D-Pantothenic acid sodium salt

MBS578469-25mg 25mg
EUR 120

D-Pantothenic acid sodium salt

MBS578469-50mg 50mg
EUR 135

D-Pantothenic acid sodium salt

MBS578469-5x200mg 5x200mg
EUR 580

D-Pantothenic acid sodium salt

MBS3609193-100mg 100mg
EUR 200

D-Pantothenic acid sodium salt

MBS3609193-200mg 200mg
EUR 225

D-Pantothenic acid sodium salt

MBS3609193-5x200mg 5x200mg
EUR 695

D-Galacturonic acid sodium salt

GC4898 5g
EUR 2061.32

D-Galacturonic acid sodium salt

GC4898-25 25
EUR 318.6

D-Galacturonic acid sodium salt

GC4898-250 250
EUR 1960.5

D-Galacturonic acid sodium salt

GC4898-5 5
EUR 135.7

D-(-)-Norgestrel Sulfate Sodium Salt

N689520 100mg
EUR 222

Neridronate, Sodium Salt (Nerixia Sodium Salt)

MBS6080862-10mg 10(mg
EUR 485

Neridronate, Sodium Salt (Nerixia Sodium Salt)

MBS6080862-5x10mg 5x10mg
EUR 2025

alpha-D-Thiomannose Sodium Salt

A576078 100mg
EUR 1800
Description: 111057-34-2

Aniline D-Glucuronide Sodium Salt

A662500 10mg
EUR 782
Description: 116866-42-3

D-Mannopyranuronic acid, sodium salt

GC5971 10mg
EUR 1323

D-Mannopyranuronic acid, sodium salt

GC5971-10 10
EUR 344.8

D-Mannopyranuronic acid, sodium salt

GC5971-100 100
EUR 1444.9

D-Mannopyranuronic acid, sodium salt

GC5971-25 25
EUR 624.6

D-Mannopyranuronic acid, sodium salt

GC5971-50 50
EUR 932.2

D-Glucuronic Acid, Sodium salt Monohydrate (Sodium D-Glucuronate)

MBS651816-100g 100g
EUR 610

D-Glucuronic Acid, Sodium salt Monohydrate (Sodium D-Glucuronate)

MBS651816-10g 10g
EUR 280
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