Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial.

Left ventricular (LV) dysfunction c-kit-positive, lineage-negative cardiac stem cells (CSC) improving post-infarction when given to animals. We conducted an experiment phase 1 (Stem Cell Infusion in Patients with ischemic cardiomyopathy [Scipio]) from autologous CSC for the treatment of heart failure due to ischemic heart disease.In trial stage A Scipio, patients with post-infarction LV dysfunction (ejection fraction [EF] ≤ 40%) prior to coronary artery bypass grafting were consecutively enrolled in the treatment and control groups. In stage B, patients were randomly assigned to treatment or control groups in a ratio of 2: 3 by using the block scheme of computer-generated randomization. 1 million autologous CSC given by intracoronary infusion at an average of 113 days (SE 4) after surgery; untreated controls.

Although this study is an open label, echocardiographic analysis did not know the duties of the group. The primary endpoint was a short-term security of CSC and the secondary endpoint was efficacy. A per-protocol analysis were used. This study is registered with ClinicalTrials.gov, number NCT00474461.This study is still in progress. 16 patients were assigned to the treatment group and seven for the control group; no side effects were reported related CSC.

On 14 CSC-treated patients were analyzed, LVEF increased from 30 · 3% (SE 1 · 9) before CSC infusion to 38 · 5% (2 · 8) at 4 months after infusion (p = 0 · 001). In contrast, the seven control patients, as long as the appropriate time interval, LVEF did not change (30 · 1% [2 · 4] at 4 months after CABG vs 30 · 2% [2 · 5] at 8 months after CABG). Importantly, CSC healthful effects are even more pronounced in the first year in eight patients (eg, LVEF increased by 12 · 3 unit ejection fraction [2 · 1] vs baseline, p = 0 · 0007).

In seven patients treated in whom cardiac MRI can be done, infarct size decreased from 32 · 6 g (6 · 3) by 7 · 8 g (1 · 7; 24%) at 4 months (p = 0 · 004) and 9 · 8 g (3 · 5; 30%) at 1 year (p = 0 · 04) .This preliminary results in patients with very encouraging. They suggest that intracoronary infusion of autologous CSC effective in improving LV systolic function and reduced infarct size in patients with heart failure after myocardial infarction, and warrant further, larger, phase 2 studies.University of Louisville Research Foundation and the National Institutes of Health ,

D-Luciferin, Sodium Salt

7902-25G each Ask for price

D-Luciferin, Sodium Salt

7902-3PK each
EUR 1110

D-Luciferin, Sodium Salt

7902-50G each Ask for price

D-Luciferin, Sodium Salt

7902-5PK each
EUR 1795.2

D-Luciferin, SODIUM SALT

10102-1 50MG
EUR 86
Description: N/A

D-Luciferin, SODIUM SALT

10102-1-1 EA
EUR 232

D-Luciferin, SODIUM SALT

10102-2 1G
EUR 799
Description: N/A

D-Luciferin, SODIUM SALT

10102-2-1 EA
EUR 799

D-Luciferin sodium salt

B8311-10 10 mg
EUR 48
Description: The substrate of firefly luciferase

D-Luciferin sodium salt

B8311-200 200 mg
EUR 344
Description: The substrate of firefly luciferase

D-Luciferin sodium salt

B8311-50 50 mg
EUR 128
Description: The substrate of firefly luciferase

D-Luciferin (sodium salt)

HY-12591 50mg
EUR 183.6

D-Luciferin sodium salt

GP8979-100 100
EUR 310.6

D-Luciferin sodium salt

GP8979-25 25
EUR 113.1

D-Luciferin,-sodium-salt

E37F12509 1-g
EUR 1333.33
Description: Reagents-for-in-vivo-imaging.Bioluminescence-reagent.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12509 25 mg
EUR 88
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12509-25mg 25 mg
EUR 86
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12510 100 mg
EUR 112
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12510-100mg 100 mg
EUR 109
Description: Luciferin is the most popular and versatile bioluminescent substrate.

D-Luciferin, sodium salt *CAS#: 103404-75-7*

12511-1g 1 g
EUR 621
Description: Luciferin is the most popular and versatile bioluminescent substrate.

Luciferin

PCT1557-100MG 1 unit
EUR 318.64
Description: Luciferin

Luciferin

PCT1557-1G 1 unit
EUR 2760.87
Description: Luciferin

Luciferin

PCT1557-250MG 1 unit
EUR 764.83
Description: Luciferin

Luciferin

PCT1557-500MG 1 unit
EUR 1453.21
Description: Luciferin

Latia luciferin

T32585-10mg 10mg Ask for price
Description: Latia luciferin

Latia luciferin

T32585-1g 1g Ask for price
Description: Latia luciferin

Latia luciferin

T32585-1mg 1mg Ask for price
Description: Latia luciferin

Latia luciferin

T32585-50mg 50mg Ask for price
Description: Latia luciferin

Latia luciferin

T32585-5mg 5mg Ask for price
Description: Latia luciferin

Cypridina luciferin

T31154-10mg 10mg Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-1g 1g Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-1mg 1mg Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-50mg 50mg Ask for price
Description: Cypridina luciferin

Cypridina luciferin

T31154-5mg 5mg Ask for price
Description: Cypridina luciferin

2,4-D sodium salt

T40324-10mg 10mg Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-1g 1g Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-1mg 1mg Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-50mg 50mg Ask for price
Description: 2,4-D sodium salt

2,4-D sodium salt

T40324-5mg 5mg Ask for price
Description: 2,4-D sodium salt

Luciferin-O-galactopyranoside

T32927-10mg 10mg Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-1g 1g Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-1mg 1mg Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-50mg 50mg Ask for price
Description: Luciferin-O-galactopyranoside

Luciferin-O-galactopyranoside

T32927-5mg 5mg Ask for price
Description: Luciferin-O-galactopyranoside

d-Cloprostenol Sodium Salt

C587330 10mg
EUR 293
Description: 62561-03-9

D-Luciferin Sodium

540277 50.0mg
EUR 180

D-Luciferin Sodium

T19743-10mg 10mg Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-1g 1g Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-1mg 1mg Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-50mg 50mg Ask for price
Description: D-Luciferin Sodium

D-Luciferin Sodium

T19743-5mg 5mg Ask for price
Description: D-Luciferin Sodium

D,L-Alanosine Sodium Salt

A510795 250mg
EUR 161

D-Mannuronic Acid Sodium Salt

D208470 1g
EUR 1200
Description: 921-56-2

D-Pantothenic Acid Sodium Salt

26004-02 25G
EUR 39.2

D-Pantothenic Acid Sodium Salt

26004-44 5G
EUR 19.25

D-Pantothenic Acid Sodium Salt

41600203-1 25 g
EUR 65.69

D-Pantothenic Acid Sodium Salt

41600203-2 100 g
EUR 169.05

D-Pantothenic Acid Sodium Salt

P190308 2.5g
EUR 80
Description: 867-81-2

D-Galacturonic acid sodium salt

GC4898-25 25
EUR 318.6

D-Galacturonic acid sodium salt

GC4898-250 250
EUR 1960.5

D-Galacturonic acid sodium salt

GC4898-5 5
EUR 135.7

D-(-)-Norgestrel Sulfate Sodium Salt

N689520 100mg
EUR 222

alpha-D-Thiomannose Sodium Salt

A576078 100mg
EUR 1800
Description: 111057-34-2

Aniline D-Glucuronide Sodium Salt

A662500 10mg
EUR 782
Description: 116866-42-3

D-Mannopyranuronic acid, sodium salt

GC5971-10 10
EUR 344.8

D-Mannopyranuronic acid, sodium salt

GC5971-100 100
EUR 1444.9

D-Mannopyranuronic acid, sodium salt

GC5971-25 25
EUR 624.6

D-Mannopyranuronic acid, sodium salt

GC5971-50 50
EUR 932.2

StayBrite? Highly Stable Luciferase/Luciferin Reagent

K790-100 each
EUR 222

StayBrite? Highly Stable Luciferase/Luciferin Reagent

K790-1000 each
EUR 1005.6

StayBrite? Highly Stable Luciferase/Luciferin Reagent

K790-10000 each
EUR 6943.2

UDP-β-D-Glucose (sodium salt)

T37899-10mg 10mg Ask for price
Description: UDP-β-D-Glucose (sodium salt)

UDP-β-D-Glucose (sodium salt)

T37899-1g 1g Ask for price
Description: UDP-β-D-Glucose (sodium salt)

UDP-β-D-Glucose (sodium salt)

T37899-1mg 1mg Ask for price
Description: UDP-β-D-Glucose (sodium salt)

UDP-β-D-Glucose (sodium salt)

T37899-50mg 50mg Ask for price
Description: UDP-β-D-Glucose (sodium salt)

UDP-β-D-Glucose (sodium salt)

T37899-5mg 5mg Ask for price
Description: UDP-β-D-Glucose (sodium salt)

1-Thio-D-Glucose Sodium Salt

T11015 1G
EUR 889.14

Firefly Luciferin 4-Monooxygenase (Recombinant)

20-abx073317
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 mg
  • 20 ug
  • 5 ug

Recombinant Firefly Luciferin 4-Monooxygenase

7-03073 5µg Ask for price

Recombinant Firefly Luciferin 4-Monooxygenase

7-03074 25µg Ask for price

Recombinant Firefly Luciferin 4-Monooxygenase

7-03075 1mg Ask for price

Luciferin 4-Monooxygenase Firefly Recombinant

rAP-1450 Inquiry Ask for price

D-Sorbose 1-Phosphate Sodium Salt

S982170 25mg
EUR 7950

D-Xylulose 5-Phosphate Sodium Salt

X750920 0.5mg
EUR 949
Description: 105931-44-0

D-Glucosamine 2-sulfate sodium salt

GC9126-25 25
EUR 30.9

D-Glucosamine 2-sulfate sodium salt

GC9126-25MG 25 mg
EUR 73.2

D-Mannose-6-phosphate Sodium Salt

M185003 10mg
EUR 58

Curcumin b-D-Glucuronide Sodium Salt

C838505 10mg
EUR 253

D-Ribulose-5-phosphate (sodium salt)

T37988-10mg 10mg Ask for price
Description: D-Ribulose-5-phosphate (sodium salt)

D-Ribulose-5-phosphate (sodium salt)

T37988-1g 1g Ask for price
Description: D-Ribulose-5-phosphate (sodium salt)

D-Ribulose-5-phosphate (sodium salt)

T37988-1mg 1mg Ask for price
Description: D-Ribulose-5-phosphate (sodium salt)

D-Ribulose-5-phosphate (sodium salt)

T37988-50mg 50mg Ask for price
Description: D-Ribulose-5-phosphate (sodium salt)

D-Ribulose-5-phosphate (sodium salt)

T37988-5mg 5mg Ask for price
Description: D-Ribulose-5-phosphate (sodium salt)

Methyl beta-D-glucuronide sodium salt

GC4190-1G 1 g
EUR 274.8

Methyl beta-D-glucuronide sodium salt

GC4190-250MG 250 mg
EUR 132

Methyl Beta-D-Glucuronide, Sodium Salt

M311550 100mg
EUR 2222

Alpha-D-Glucoheptonic Acid Sodium Salt

G450165 100g
EUR 63
Description: 10094-62-9

Epinephrine β-D-Glucuronide Sodium Salt

E912560 10mg
EUR 1533
Description: NA

D-Glucuronic acid sodium salt monohydrate

GC8431-100 100
EUR 95

D-Glucuronic acid sodium salt monohydrate

GC8431-100G 100 g
EUR 151.2

D-Glucuronic acid sodium salt monohydrate

GC8431-25 25
EUR 39.4

D-Glucuronic acid sodium salt monohydrate

GC8431-250 250
EUR 197.7

D-Glucuronic acid sodium salt monohydrate

GC8431-250G 250 g
EUR 274.8

D-Glucuronic acid sodium salt monohydrate

GC8431-25G 25 g
EUR 84

D-Glucuronic acid sodium salt monohydrate

GC8431-5 5
EUR 15.9

D-Glucuronic acid sodium salt monohydrate

GC8431-5G 5 g
EUR 55.2

D-Glucuronic acid, sodium salt, monohydrate

GB0483 5g
EUR 128.9

Alpha-Methyl-D-tryptophan Sodium Salt

M331990 250mg
EUR 184

D-Glucuronic acid sodium salt monohydrate

T5068-10mg 10mg Ask for price
Description: D-Glucuronic acid sodium salt monohydrate

D-Glucuronic acid sodium salt monohydrate

T5068-1g 1g Ask for price
Description: D-Glucuronic acid sodium salt monohydrate

D-Glucuronic acid sodium salt monohydrate

T5068-1mg 1mg Ask for price
Description: D-Glucuronic acid sodium salt monohydrate

D-Glucuronic acid sodium salt monohydrate

T5068-50mg 50mg Ask for price
Description: D-Glucuronic acid sodium salt monohydrate

D-Glucuronic acid sodium salt monohydrate

T5068-5mg 5mg Ask for price
Description: D-Glucuronic acid sodium salt monohydrate

N-D-Glucopyranosyl-glycine Sodium Salt

G425060 500mg
EUR 667
Description: 117072-57-8

Resorufin beta-D-Glucuronide Sodium Salt

R146513 100mg
EUR 1800
Description: 125440-91-7

Betamethasone b-D-Glucuronide Sodium Salt

B327010 10mg
EUR 184
Description: 105088-07-1

Formononetin-b-D-glucuronide sodium salt

GC1919-10 10
EUR 354.2

Formononetin-b-D-glucuronide sodium salt

GC1919-25 25
EUR 661.8

Formononetin-b-D-glucuronide sodium salt

GC1919-5 5
EUR 251.8

Formononetin-b-D-glucuronide sodium salt

GC1919-50 50
EUR 1072

1-thio-β-D-Glucose (sodium salt)

T37786-10mg 10mg Ask for price
Description: 1-thio-β-D-Glucose (sodium salt)

1-thio-β-D-Glucose (sodium salt)

T37786-1g 1g Ask for price
Description: 1-thio-β-D-Glucose (sodium salt)

1-thio-β-D-Glucose (sodium salt)

T37786-1mg 1mg Ask for price
Description: 1-thio-β-D-Glucose (sodium salt)

1-thio-β-D-Glucose (sodium salt)

T37786-50mg 50mg Ask for price
Description: 1-thio-β-D-Glucose (sodium salt)

1-thio-β-D-Glucose (sodium salt)

T37786-5mg 5mg Ask for price
Description: 1-thio-β-D-Glucose (sodium salt)

Dexamethasone Beta-D-Glucuronide Sodium Salt

D298810 10mg
EUR 230
Description: 105088-08-2

4-Demethyltrimethoprim Sulfate Sodium Salt-D₆

D112562 100mg
EUR 7600

Luciferin 4-Monooxygenase Firefly Recombinant, Active

rAP-1446 Inquiry Ask for price

D-Psicose 6-Phosphate Sodium Salt (~90%)

P839655 10mg
EUR 234

UDP-α-D-Glucose (sodium salt hydrate)

T37898-10mg 10mg Ask for price
Description: UDP-α-D-Glucose (sodium salt hydrate)

UDP-α-D-Glucose (sodium salt hydrate)

T37898-1g 1g Ask for price
Description: UDP-α-D-Glucose (sodium salt hydrate)

UDP-α-D-Glucose (sodium salt hydrate)

T37898-1mg 1mg Ask for price
Description: UDP-α-D-Glucose (sodium salt hydrate)

UDP-α-D-Glucose (sodium salt hydrate)

T37898-50mg 50mg Ask for price
Description: UDP-α-D-Glucose (sodium salt hydrate)

UDP-α-D-Glucose (sodium salt hydrate)

T37898-5mg 5mg Ask for price
Description: UDP-α-D-Glucose (sodium salt hydrate)

Luciferase Luciferin 4-Monooxygenase Firefly Recombinant Protein

PROTP08659 Regular: 20ug
EUR 380.4
Description: Luciferase produced in E.Coli is a single, non-glycosylated polypeptide chain containing 571 amino acids (1-550 a.a.) and having a molecular mass of 62.9kDa.;Luciferase is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

D-Mannose-6-O-sulphate Sodium Salt

M185013 10mg
EUR 959
Description: 204575-08-6

Codeine 6-b-D-Glucuronide Sodium Salt

C634090 10mg
EUR 187

1-Thio-Beta-D-galactose Sodium Salt

T350500 250mg
EUR 115

Estriol 3-β-D-Glucuronide (sodium salt)

T37005-10mg 10mg Ask for price
Description: Estriol 3-β-D-Glucuronide (sodium salt)

Estriol 3-β-D-Glucuronide (sodium salt)

T37005-1g 1g Ask for price
Description: Estriol 3-β-D-Glucuronide (sodium salt)

Estriol 3-β-D-Glucuronide (sodium salt)

T37005-1mg 1mg Ask for price
Description: Estriol 3-β-D-Glucuronide (sodium salt)

Estriol 3-β-D-Glucuronide (sodium salt)

T37005-50mg 50mg Ask for price
Description: Estriol 3-β-D-Glucuronide (sodium salt)

Estriol 3-β-D-Glucuronide (sodium salt)

T37005-5mg 5mg Ask for price
Description: Estriol 3-β-D-Glucuronide (sodium salt)

MES SODIUM SALT

213002 each Ask for price

NAD Sodium Salt

40190036-1 1 g
EUR 126.75

NAD Sodium Salt

40190036-2 5 g
EUR 209.25

NAD Sodium Salt

40190036-3 25 g
EUR 573.75

MES Sodium Salt

41320069-1 100 g
EUR 38.69

MES Sodium Salt

41320069-2 250 g
EUR 90.52

MES Sodium Salt

41320069-3 500 g
EUR 169.29

MES Sodium Salt

41320069-4 50 g
EUR 27.69

ADA Sodium Salt

40100302-1 50 g
EUR 36

ADA Sodium Salt

40100302-2 100 g
EUR 64.49

MES sodium salt

C6532-1000 1g
EUR 68

MES sodium salt

C6532-500 500mg
EUR 44
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